In the first part of this paper, we will consider minimizing configurations of the Oseen-Frank energy functional $E(n, m)$ for a biaxial nematics $(n, m):Omegato mathbb S^2times mathbb S^2$ with $ncdot m=0$ in dimension three, and establish that it is smooth off a closed set of $1$-dimension Hausdorff measure zero. In the second part, we will consider a simplified Ericksen-Leslie system for biaxial nematics $(n, m)$ in a two dimensional domain and establish the existence of a unique global weak solution $(u, n, m)$ that is smooth off at most finitely many singular times for any initial and boundary data of finite energy. They extend to biaxial nematics of earlier results corresponding to minimizing uniaxial nematics by Hardt-Kindelerherer-Lin cite{HKL} and a simplified hydrodynamics of uniaxial liquid crystal by Lin-Lin-Wang cite{LLW10} respectively.