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Calcified plaque in the aorta and pelvic arteries is associated with coronary artery calcification and is a strong predictor of heart attack. Current calcified plaque detection models show poor generalizability to different domains (ie. pre-contrast vs. post-contrast CT scans). Many recent works have shown how cross domain object detection can be improved using an image translation model which translates between domains using a single shared latent space. However, while current image translation models do a good job preserving global/intermediate level structures they often have trouble preserving tiny structures. In medical imaging applications, preserving small structures is important since these structures can carry information which is highly relevant for disease diagnosis. Recent works on image reconstruction show that complex real-world images are better reconstructed using a union of subspaces approach. Since small image patches are used to train the image translation model, it makes sense to enforce that each patch be represented by a linear combination of subspaces which may correspond to the different parts of the body present in that patch. Motivated by this, we propose an image translation network using a shared union of subspaces constraint and show our approach preserves subtle structures (plaques) better than the conventional method. We further applied our method to a cross domain plaque detection task and show significant improvement compared to the state-of-the art method.
Current deep learning based segmentation models often generalize poorly between domains due to insufficient training data. In real-world clinical applications, cross-domain image analysis tools are in high demand since medical images from different d
State-of-the-art techniques in Generative Adversarial Networks (GANs) have shown remarkable success in image-to-image translation from peer domain X to domain Y using paired image data. However, obtaining abundant paired data is a non-trivial and exp
The focus of this paper is on detection theory for union of subspaces (UoS). To this end, generalized likelihood ratio tests (GLRTs) are presented for detection of signals conforming to the UoS model and detection of the corresponding active subspace
Image-to-image translation tasks have been widely investigated with Generative Adversarial Networks (GANs). However, existing approaches are mostly designed in an unsupervised manner while little attention has been paid to domain information within u
We propose a general framework for unsupervised domain adaptation, which allows deep neural networks trained on a source domain to be tested on a different target domain without requiring any training annotations in the target domain. This is achieve