Recent results from multi-wavelength observations of the inner few hundred pc of the Galactic center have added two new characteristics to the ISM in this unique region. One is the cosmic ray ionization rate derived from H$_3^+$ measurements is at least two orders of magnitudes higher than in the disk of the Galaxy. The other is the bipolar thermal X-ray and synchrotron emission from this region, suggesting a relic of past activity. We propose that the high cosmic ray pressure drives a large-scale wind away from the Galactic plane and produces the bipolar emission as well as highly blue-shifted diffuse gas detected in H$_3^+$ absorption studies. We then discuss the interaction of large-scale winds with a number of objects, such as cloudlets and stellar wind bubbles, to explain the unusual characteristics of the ISM in this region including the nonthermal radio filaments. One of the implications of this scenario is the removal of gas driven by outflowing winds may regulate star formation or black hole accretion.