Let $X$ be a real prehomogeneous vector space under a reductive group $G$, such that $X$ is an absolutely spherical $G$-variety with affine open orbit. We define local zeta integrals that involve the integration of Schwartz-Bruhat functions on $X$ against generalized matrix coefficients of admissible representations of $G(mathbb{R})$, twisted by complex powers of relative invariants. We establish the convergence of these integrals in some range, the meromorphic continuation as well as a functional equation in terms of abstract $gamma$-factors. This subsumes the Archimedean zeta integrals of Godement-Jacquet, those of Sato-Shintani (in the spherical case), and the previous works of Bopp-Rubenthaler. The proof of functional equations is based on Knops results on Capelli operators.