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This work reports on a study to develop a patient-specific finite element model of the Transcatheter Aortic Valve Implantation procedure, using a model of a balloon-expandable percutaneous prosthetic aortic valve as a framework for the prediction of its performance. An experimentally measured left ventricle and aortic pressure profile of a single systolic-diastolic cycle of a resting heart are used to assess the performance of the stent after its deployment. The results of the simulation show that the stent maintains its structural integrity after deployment, and successfully pushes the native leaflets back to keep the aortic root clear of all impediments.
This paper presents a new method for modeling the mechanics of the aortic valve, and simulates its interaction with blood. As much as possible, the model construction is based on first principles, but such that the model is consistent with experiment
An arteriovenous fistula, created by artificially connecting segments of a patients vasculature, is the preferred way to gain access to the bloodstream for kidney dialysis. The increasing power and availability of supercomputing infrastructure means
A patient-specific fluid-structure interaction (FSI) model of a phase-contrast magnetic resonance angiography (PC-MRA) imaged arteriovenous fistula is presented. The numerical model is developed and simulated using a commercial multiphysics simulatio
In its permanent quest of mechanobiological homeostasis, our vascula-ture significantly adapts across multiple length and time scales in various physiological and pathological conditions. Computational modeling of vascular growth and remodeling (G&R)
Invasive intracranial electroencephalography (iEEG) or electrocorticography (ECoG) measures electrical potential directly on the surface of the brain, and, combined with numerical modeling, can be used to inform treatment planning for epilepsy surger