We consider the effect of higher twist operators of the Wilson operator product expansion in the structure function $F_{2}(x,Q^{2})$ at small-$x$, taking into account QCD effective charges whose infrared behavior is constrained by a dynamical mass scale. The higher twist corrections are obtained from the renormalon formalism. Our analysis is performed within the conventional framework of next-to-leading order, with the factorization and renormalization scales chosen to be $Q^{2}$. The infrared properties of QCD are treated in the context of the generalized double-asymptotic-scaling approximation. We show that the corrections to $F_{2}$ associated with twist-four and twist-six are both necessary and sufficient for a good description of the deep infrared experimental data.
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