We study the problem of when triangulated categories admit unique infinity-categorical enhancements. Our results use Luries theory of prestable infinity-categories to give conceptual proofs of, and in many cases strengthen, previous work on the subject by Lunts--Orlov and Canonaco--Stellari. We also give a wide range of examples involving quasi-coherent sheaves, categories of almost modules, and local cohomology to illustrate the theory of prestable infinity-categories. Finally, we propose a theory of stable $n$-categories which would interpolate between triangulated categories and stable infinity-categories.