General Two Higgs Doublet Models (2HDM) are popular Standard Model extensions but feature flavor changing interactions and lack neutrino masses. We discuss a 2HDM where neutrino masses are generated via type I seesaw and propose an extension where neutrino masses are generated via a type II seesaw mechanism with flavor changing interactions being absent via the presence of a U(1) gauge symmetry. After considering a variety of bounds such as those rising from collider and electroweak precision we show that our proposal stands as a UV complete 2HDM with a dark photon where neutrino masses and flavor changing interactions are addressed. A possible dark matter realization is also discussed.