We evaluate the effect of quantum electrodynamics on the correlations between Dirac field modes corresponding electron-positron pairs of opposite momenta generated by expansion of an asymptotically flat Friedmann-Robertson-Walker (FRW) universe. The mutual information of out-going electron-positron pairs is evaluated to leading order in the coupling strength and compared with the free case. It is shown a decrease in the mutual information between the electron and positron. In addition, it is found that the change in the electron-positron mutual information depends on how the momentum is distributed between the positron and photon modes.