Recently reported coincidences between high-energy neutrino events and major blazar outbursts reinforce the relevance of lepto-hadronic emission models for blazars. We study the influence of physical parameters on the neutrino output modeling blazar spectral energy distributions self-consistently assuming a relativistically propagating acceleration zone surrounded by a larger cooling zone. We find that the gross features of the spectral energy distribution can readily be explained with the model. A rigorous test requires time-resolved measurements of blazar spectral energy distributions during an outburst and high-statistics neutrino measurements to discriminate the leptonic and hadronic emission components.
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