Nuggets---very large stable bound objects arising in the presence of a sufficiently attractive and long-range force and in the absence of a dark Coulomb force---are a smoking gun signature for Asymmetric Dark Matter (ADM). The cosmology of ADM nuggets is both generic and unique: nuggets feature highly exothermic fusion processes, which can impact the shape of the core in galaxies, as well as give rise to rare dark star formation. We find, considering the properties of nuggets in a generic extended nuclear model with both attractive and repulsive forces, that self-interaction constraints place an upper bound on nugget masses at the freeze-out of synthesis in the ballpark of $M_{rm fo} lesssim 10^{16}$ GeV. We also show that indirect detection strongly constrains models where the scalar mediator binding the nuggets mixes with the Higgs.
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