In high reliability standards fields such as automotive, avionics or aerospace, the detection of anomalies is crucial. An efficient methodology for automatically detecting multivariate outliers is introduced. It takes advantage of the remarkable properties of the Invariant Coordinate Selection (ICS) method. Based on the simultaneous spectral decomposition of two scatter matrices, ICS leads to an affine invariant coordinate system in which the Euclidian distance corresponds to a Mahalanobis Distance (MD) in the original coordinates. The limitations of MD are highlighted using theoretical arguments in a context where the dimension of the data is large. Unlike MD, ICS makes it possible to select relevant components which removes the limitations. Owing to the resulting dimension reduction, the method is expected to improve the power of outlier detection rules such as MD-based criteria. It also greatly simplifies outliers interpretation. The paper includes practical guidelines for using ICS in the context of a small proportion of outliers which is relevant in high reliability standards fields. The choice of scatter matrices together with the selection of relevant invariant components through parallel analysis and normality tests are addressed. The use of the regular covariance matrix and the so called matrix of fourth moments as the scatter pair is recommended. This choice combines the simplicity of implementation together with the possibility to derive theoretical results. A simulation study confirms the good properties of the proposal and compares it with other scatter pairs. This study also provides a comparison with Principal Component Analysis and MD. The performance of our proposal is also evaluated on several real data sets using a user-friendly R package accompanying the paper.