We investigate the role of quantum coherence depletion (QCD) in Grover search algorithm (GA) by using several typical measures of quantum coherence and quantum correlations. By using the relative entropy of coherence measure ($mathcal{C}_r$), we show that the success probability depends on the QCD. The same phenomenon is also found by using the $l_1$ norm of coherence measure ($mathcal{C}_{l_1}$). In the limit case, the cost performance is defined to characterize the behavior about QCD in enhancing the success probability of GA, which is only related to the number of searcher items and the scale of database, no matter using $mathcal{C}_r$ or $mathcal{C}_{l_1}$. In generalized Grover search algorithm (GGA), the QCD for a class of states increases with the required optimal measurement time. In comparison, the quantification of other quantum correlations in GA, such as pairwise entanglement, multipartite entanglement, pairwise discord and genuine multipartite discord, cannot be directly related to the success probability or the optimal measurement time. Additionally, we do not detect pairwise nonlocality or genuine tripartite nonlocality in GA since Clauser-Horne-Shimony-Holt inequality and Svetlichnys inequality are not violated.