We propose a scheme to modulate the entanglement between two oscillators separated in space via the squeezing cavity field generated by the optical parametric amplifier instead of injecting the squeezing field directly with the assistance of Coulomb interaction. We show that the Coulomb interaction between the oscillators is the essential reason for the existence of entanglement. Due to the gain of the optical parametric amplifier and the phase of the pump driving the optical parametric amplifier can simultaneously modulate the squeezing cavity field, the radiation pressure interaction between the cavity field and the oscillator is modulated accordingly. We find that there is competing effect between the radiation pressure interaction and the Coulomb interaction for the oscillator which these two interactions act on simultaneously. Therefore, the modulation of entanglement can be achieved with the assistance of Coulomb interaction. The results of numerical simulation show that the present scheme has stronger robustness against the temperature of environment compared with previous schemes in experimentally feasible regimes.