The disk around HD 142527 attracts a lot of attention, amongst others because of its resolved (sub) mm dust continuum that is concentrated into a horseshoe-shape towards the north of the star. In this manuscript we present spatially resolved ALMA detections of the HCN J=4-3 and CS J=7-6 emission lines. These lines give us a view deeper into the disk compared to the (optically thicker) CO isotopes. This is the first detection of CS J=7-6 coming from a protoplanetary disk. Both emission lines are azimuthally asymmetric and are suppressed under the horseshoe-shaped continuum emission peak. A possible mechanism to explain the decrease under the horseshoe-shaped continuum is the increased opacity coming from the higher dust concentration at the continuum peak. Lower {gr dust and/or gas} temperatures and an optically thick radio-continuum reduce line emission by freeze-out and shielding of emission from the far side of the disk.
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