We study a quantum quench in the Bose-Hubbard model where the tunneling rate $J$ is suddenly switched from zero to a finite value in the Mott regime. In order to solve the many-body quantum dynamics far from equlibrium, we consider the reduced density matrices for a finite number (one, two, three, etc.) of lattice sites and split them up into on-site density operators, i.e., the mean field, plus two-point and three-point correlations etc. Neglecting three-point and higher correlations, we are able to numerically simulate the time-evolution of the few-site density matrices and the two-point quantum correlations (e.g., their effective light-cone structure) for a comparably large number ${cal O}(10^3)$ of lattice sites.