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Synaptic metaplasticity underlies tetanic potentiation in Lymnaea: a novel paradigm

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 نشر من قبل Anita Mehta
 تاريخ النشر 2013
  مجال البحث فيزياء
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We present a mathematical model which explains and interprets a novel form of short-term potentiation, which was found to be use-, but not time-dependent, in experiments done on Lymnaea neurons. The high degree of potentiation is explained using a model of synaptic metaplasticity, while the use-dependence (which is critically reliant on the presence of kinase in the experiment) is explained using a model of a stochastic and bistable biological switch.



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