We formulate a novel approach to decoherence based on neglecting observationally inaccessible correlators. We apply our formalism to a renormalised interacting quantum field theoretical model. Using out-of-equilibrium field theory techniques we show that the Gaussian von Neumann entropy for a pure quantum state increases to the interacting thermal entropy. This quantifies decoherence and thus measures how classical our pure state has become. The decoherence rate is equal to the single particle decay rate in our model. We also compare our approach to existing approaches to decoherence in a simple quantum mechanical model. We show that the entropy following from the perturbative master equation suffers from physically unacceptable secular growth.