We study the production and decay of fourth generation leptons at the Large Hadron Collider (LHC).We find that for charged leptons with masses under a few hundred GeV, the dominant collider signal comes from the production through a W-boson of a charged and neutral fourth generation lepton. We present a sensitivity study for this process in events with two like-sign charged leptons and at least two associated jets. We show that with sqrts = 7 TeV and 1 inverse fb of data, the LHC can exclude fourth generation charged leptons with masses up to 250 GeV.