We report studies on pressure dependence of superconducting transition temperature (Tc) of LaFeAsO, LaFeAs(O0.5F0.5) and LaFeAs(O0.89F0.11) samples. In-situ resistance measurements under high pressure showed that the Tc of these three compounds increases with pressure initially, reaches a maximum value and then decreases with further increasing pressure, although the Tc at ambient pressure are different. The onset Tc of LaFeAsO is ~50 K at 1.5 GPa, which is the highest record in La-based oxypnicited system. The significant change in Tc induced by pressure is attributed to the orbital degeneracy and the electron density of state at the Fermi level.
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