Peculiar velocities of clusters of galaxies can be measured by studying the fluctuations in the cosmic microwave background (CMB) generated by the scattering of the microwave photons by the hot X-ray emitting gas inside clusters. While for individual clusters such measurements result in large errors, a large statistical sample of clusters allows one to study cumulative quantities dominated by the overall bulk flow of the sample with the statistical errors integrating down. We present results from such a measurement using the largest all-sky X-ray cluster catalog combined to date and the 3-year WMAP CMB data. We find a strong and coherent bulk flow on scales out to at least > 300 h^{-1} Mpc, the limit of our catalog. This flow is difficult to explain by gravitational evolution within the framework of the concordance LCDM model and may be indicative of the tilt exerted across the entire current horizon by far-away pre-inflationary inhomogeneities.
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