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Self-organized periodicity of protein clusters in growing bacteria

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 نشر من قبل Hui Wang
 تاريخ النشر 2008
  مجال البحث فيزياء
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Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using flourrescence imaging have shown that, during cell growth, lateral clusters form at positions approximately periodically spaced along the cell body. In this paper, we demonstrate within a lattice model that such spatial organization could arise spontaneously from a stochastic nucleation mechanism. The same mechanism may explain the recent observation of periodic aggregates of misfolded proteins in E. coli.



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