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Blood system functions are very diverse and important for most processes in human organism. One of its primary functions is matter transport among different parts of the organism including tissue supplying with oxygen, carbon dioxide excretion, drug propagation etc. Forecasting of these processes under normal conditions and in the presence of different pathologies like atherosclerosis, loss of blood, anatomical abnormalities, pathological changing in chemical transformations and others is significant issue for many physiologists. In this connection should be pointed out that global processes are of special interest as they include feedbacks and interdependences among different regions of the organism. Thus the main goal of this work is to develop the model allowing to describe effectively blood flow in the whole organism. As we interested in global processes the models of the four vascular trees (arterial and venous parts of systemic and pulmonary circulation) must be closed with heart and peripheral circulation models. As one of the model applications the processes of the blood loss is considered in the end of the paper.
Numerical model of the peripheral circulation and dynamical model of the large vessels and the heart are discussed in this paper. They combined together into the global model of blood circulation. Some results of numerical simulations concerning matt
The hearts, kidneys, livers, spleens and brains of ${}^57$Fe enriched wild-type and heterozygous $beta$-thalassaemic mice at 1, 3, 6 and 9 months of age were studied by means of Mossbauer Spectroscopy at 80K. Ferritin-like iron depositions in the hea
The goal of immunotherapy is to enhance the ability of the immune system to kill cancer cells. Immunotherapy is more effective and, in general, the prognosis is better, when more immune cells infiltrate the tumor. We explore the question of whether t
A three-dimensional unilateral contact problem for articular cartilage layers attached to subchondral bones shaped as elliptic paraboloids is considered in the framework of the biphasic cartilage model. The main novelty of the study is in accounting
Despite numerous advances in the field of tissue engineering and regenerative medicine, monitoring the formation of tissue regeneration and its metabolic variations during culture is still a challenge and mostly limited to bulk volumetric assays. Her