The study seeks to identify the role of HR empowerment and its impact on Citizenship Behavior. To achieve this objective, a standard questionnaire was adopted, adjusted and used. After having data dealt using appropriate statistical methods, the most important results showed a low level of exercise to enable the human resource empowerment at the directorates of Damascus University, and the absence of the organizational citizenship behavior among employees. It showed also a significant positive impact between elements of empowerment in general and organizational citizenship. The effect appears significantly in motivation component. Based on those results, the study suggest some recommendations.